EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.1.3.14 | 2',3'-dialdehydro-ADP | efficient inhibition is most likely due to the structural similarity to o-UDP and not to an allosteric effect via the ATP binding site | Rattus norvegicus | |
5.1.3.14 | 2',3'-dialdehydro-UDP | binds to the active site of the enzyme | Rattus norvegicus | |
5.1.3.14 | 2',3'-dialdehydro-UDP-alpha-D-N-acetylglucosamine | 0.05 mM, 70% inhibition after 30 min. 0.25 mM, 90% inhibition. Covalently bound to amino acids in the active site causing an irreversible inhibition. Effective inhibitor may serve as a basis for the chemical synthesis of further inhibitors | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.1.3.14 | Rattus norvegicus | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.1.3.14 | additional information | enzyme catalyzes the first step in synthesis of sialic acids | Rattus norvegicus | ? | - |
? |